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Pizza Casserole with Biscuits

close up shot of pizza casserole with biscuits in a clear baking dish
Quick and easy, this delicious homemade pizza casserole is a fun play on everyone’s favorite food. In under an hour you’ll have a filling, saucey, and cheesy dish that no one will turn down.
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Table of Contents
  1. INGREDIENTS FOR PIZZA CASSEROLE WITH BISCUITS
  2. HOW TO MAKE THIS PIZZA CASSEROLE WITH BISCUITS RECIPE
  3. STORAGE
  4. MORE RECIPES YOU'LL LOVE
  5. JUMP TO RECIPE

This delicious pizza casserole with biscuits is a simple family favorite that everyone loves. It’s hearty and filling, with classic pizza flavors. Made with flaky biscuits, pizza sauce, cheese, and pepperoni baked in a casserole dish, this fun spin on classic Italian cuisine is sure to please. 

Everyone loves pizza, and we love any recipe that is a spin on this favorite. These Pizza Muffins and this Upside Down Pizza Casserole are two more unique pizza recipes that have the classic flavors everyone loves.

close up shot of pizza casserole with biscuits in a clear baking dish

MORE PIZZA RECIPES:
Pizza Casserole | Stuffed Crust Pizza


INGREDIENTS FOR PIZZA CASSEROLE WITH BISCUITS

pizza casserole with biscuits process shot

You will need: 

  • 16.3 ounce can Grands! Southern Homestyle Biscuits, 8 big biscuits
  • 14 ounce jar pizza sauce
  • 1 teaspoon Italian seasoning, divided
  • 2 ½ cups shredded mozzarella cheese
  • 5 ounce of pepperoni slices
  • Pinch of red pepper flakes, optional

SUBSTITUTIONS AND ADDITIONS

Sauce: You can use any brand of pizza sauce that you prefer for this casserole. Likewise, if you have a homemade sauce recipe, that would work as well.

Toppings: Feel free to add any of your favorite pizza toppings and get creative with this casserole. Some of our favorite additions are peppers, mushrooms, olives, and onions.

Red Pepper Flakes: Sprinkling your casserole with a pinch of red pepper flakes is an optional addition that will give the dish a nice kick.

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HOW TO MAKE THIS PIZZA CASSEROLE WITH BISCUITS RECIPE

STEP ONE: Preheat the oven to 375 degrees F.

STEP TWO: Cut each biscuit into 8 pieces. Then spread biscuit pieces in a greased 9 x 13 casserole dish.

pizza casserole with biscuits process shot

STEP THREE: Pour ½ jar of pizza sauce and ½ teaspoon Italian seasoning over biscuits and stir to thoroughly coat all the biscuit pieces with a bit of sauce.

pizza casserole with biscuits process shot

STEP FOUR: Sprinkle about 1 cup of the cheese over the biscuit mixture and stir again to distribute evenly.

STEP FIVE: Pour the remaining jar of pizza sauce over the biscuit mixture.

STEP SIX: Top with remaining cheese and pepperoni. You may not need/want to use all of it, but you can for extra cheesy.

STEP SEVEN: Sprinkle remaining ½ teaspoon of Italian seasoning over the casserole.

pizza casserole with biscuits process shot

STEP EIGHT: Bake for 20 to 25 minutes or until the biscuits have puffed and the cheese is melted and beginning to brown.

pizza casserole with biscuits process shot

STEP NINE: Remove from the oven and serve immediately.

STORAGE

IN THE FRIDGE: Store casserole covered, for 2 to 3 days in the refrigerator. 

IN THE FREEZER: You can keep leftovers wrapped in an airtight container for up to 3 months in the freezer.

close up shot of pizza casserole with biscuits in a white bowl

This recipe is the perfect dinner option for busy weeknights. Add any of your favorite pizza toppings to make this just the way your family likes it. Then, serve alongside a crisp, fresh salad and you have a full meal that everyone will enjoy.

MORE RECIPES YOU’LL LOVE

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close up shot of pizza casserole with biscuits in a clear baking dish

Pizza Casserole with Biscuits

5 from 1 vote
Quick and easy, this delicious homemade pizza casserole is a fun play on everyone’s favorite food. In under an hour you’ll have a filling, saucey, and cheesy dish that no one will turn down.
Prep Time 10 minutes
Cook Time 25 minutes
Total Time 35 minutes
Servings 9

Ingredients
  

  • 16.3 oz can Grands! Southern Homestyle Biscuits 8 big biscuits
  • 14 oz jar pizza sauce
  • 1 tsp italian seasoning divided
  • 2 1/2 cup shredded mozzarella cheese
  • 5 oz pepperoni slices
  • pinch red pepper flakes optional

Instructions
 

  • Preheat the oven to 375 degrees F. 
  • Cut each biscuit into 8 pieces.
  • Spread biscuit pieces in a greased 9 x 13 casserole dish.
  • Pour ½ jar of pizza sauce and ½ teaspoon Italian seasoning over biscuits. Then stir to thoroughly coat all the biscuit pieces with a bit of sauce.
  • Sprinkle about 1 cup of the cheese over the biscuit mixture and stir again to distribute evenly.
  • Pour remaining jar of pizza sauce over the biscuit mixture.
  • Top with remaining cheese and pepperoni. You may not need/want to use all of it, but you can for extra cheesy.
  • Sprinkle red pepper flakes (desired amount) and remaining ½ teaspoon of Italian seasoning over the of the casserole.
  • Bake for 20 to 25 minutes or until the biscuits have puffed and the cheese is melted and beginning to brown.
  • Remove from oven and serve immediately.

Nutrition

Calories: 370kcal | Carbohydrates: 28g | Protein: 14g | Fat: 22g | Saturated Fat: 8g | Cholesterol: 42mg | Sodium: 1187mg | Potassium: 329mg | Fiber: 1g | Sugar: 4g | Vitamin A: 401IU | Vitamin C: 3mg | Calcium: 195mg | Iron: 3mg
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Proudly Prepared by the Spaceships Kitchen

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